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Gentaur's Products: Quality diagnostic kits, Enzymatic Assays, ELISA Kits, One-Step Rapid Tests and Chemistry Reagents


 

Alpha-L-Fucosidase (AFU) Assay Kit (liquid stable)
Product Alpha-L-Fucosidase (AFU) Assay Kit (liquid stable)
Catalog Number BQ 082A-EALD
Quantity 200 Tests
Sample Type Serum
Description
The α-L-fucosidase (AFU) assay kit is for the determination of AFU activity in patient serum samples. AFU is a lysosomal enzyme involved in the degradation of a diverse group of naturally occurring fucoglycoconjugates. Serum AFU activity is considered a useful marker of hepatocellular carcinoma (HCC). Increased AFU levels in serum are an early indication of HCC. Though measurement of serum fetoprotein (AFP) is a common practice for early detection of HCC, AFP assay alone suffers from its low specificity and sensitivity due to the fact that not all HCC secrete AFP. AFP levels may be normal in as many as 40% of patients with early HCC and 15-20% patients with advanced HCC. Recent studies clearly demonstrated that measurements of both AFP and AFU could significantly increase the detection specificity and sensitivity for HCC. AFU is reported to be a more sensitive marker especially for detecting a small tumor size of HCC.
Species Human